Searchable abstracts of presentations at key conferences in endocrinology

ea0077lb26 | Late Breaking | SFEBES2021

A microfluidics approach of mimicking an obese maternal metabolic environment identifies modified pathways in the endometrial epithelium that may be important for implantation

Tinning Haidee , Baik Soo Young , de Vasconcelos Elton , Forde Niamh

Women who are obese are more likely to suffer early pregnancy loss. Once factor that can contribute to this is endometrial dysfunction however, we are limited in our understanding of how stressors or treatments, may alter endometrial function. Mimicking the dynamic in vivo exposure of the endometrium to these stressors is difficult using in vitro static culture systems. The aim of this study was to use a microfluidic approach to mimic exposure of the endometr...